Genome-Wide Study of Gene Variants Associated with Differential Cardiovascular Event Reduction by Pravastatin Therapy

Statin therapy reduces the risk of coronary heart disease (CHD), however, the person-to-person variability in response to statin therapy is not well understood. We have investigated the effect of genetic variation on the reduction of CHD events by pravastatin. First, we conducted a genome-wide assoc...

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Detalhes bibliográficos
Main Authors: Shiffman, Dov, Trompet, Stella, Louie, Judy Z., Rowland, Charles M., Catanese, Joseph J., Iakoubova, Olga A., Kirchgessner, Todd G., Westendorp, Rudi G. J., de Craen, Anton J. M., Slagboom, P. Eline, Buckley, Brendan M., Stott, David J., Sattar, Naveed, Devlin, James J., Packard, Christopher J., Ford, Ian, Sacks, Frank M., Jukema, J. Wouter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364212/
https://ncbi.nlm.nih.gov/pubmed/22666496
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038240
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