Down-regulation of KRAS-interacting miRNA-143 predicts poor prognosis but not response to EGFR-targeted agents in colorectal cancer

BACKGROUND: MicroRNA-143 (miRNA-143) is frequently down-regulated in colorectal cancer (CRC) and may influence CRC cell proliferation, apoptosis and sensitivity to 5-fluorouracil. mRNA encoded by the KRAS oncogene has been identified as a target of miRNA-143. However, the prognostic significance of...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Pichler, M, Winter, E, Stotz, M, Eberhard, K, Samonigg, H, Lax, S, Hoefler, G
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Molecular Diagnostics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3364114/
https://ncbi.nlm.nih.gov/pubmed/22549179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2012.175
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados