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Hypoxia-inducible factor 1 protects hypoxic astrocytes against glutamate toxicity

Stroke is a major neurological disorder characterized by an increase in the Glu (glutamate) concentration resulting in excitotoxicity and eventually cellular damage and death in the brain. HIF-1 (hypoxia-inducible factor-1), a transcription factor, plays an important protective role in promoting cel...

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Detalhes bibliográficos
Main Authors: Badawi, Yomna, Ramamoorthy, Prabhu, Shi, Honglian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Neurochemistry 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3363983/
https://ncbi.nlm.nih.gov/pubmed/22540931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/AN20120006
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