Inhibition of Adult Neurogenesis by Inducible and Targeted Deletion of ERK5 Mitogen-Activated Protein Kinase Specifically in Adult Neurogenic Regions Impairs Contextual Fear Extinction and Remote Fear Memory

Although there is evidence suggesting that adult neurogenesis may contribute to hippocampus-dependent memory, signaling mechanisms responsible for adult hippocampal neurogenesis are not well characterized. Here we report that ERK5 mitogen-activated protein kinase is specifically expressed in the neu...

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Main Authors: Pan, Yung-Wei, Chan, Guy C. K., Kuo, Chay T., Storm, Daniel R., Xia, Zhengui
פורמט: Artigo
שפה:Inglês
יצא לאור: Society for Neuroscience 2012
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Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3363363/
https://ncbi.nlm.nih.gov/pubmed/22573667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.6076-11.2012
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