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Response to DNA damage of CHEK2 missense mutations in familial breast cancer
Comprehensive sequencing of tumor suppressor genes to evaluate inherited predisposition to cancer yields many individually rare missense alleles of unknown functional and clinical consequence. To address this problem for CHEK2 missense alleles, we developed a yeast-based assay to assess in vivo CHEK...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3363333/ https://ncbi.nlm.nih.gov/pubmed/22419737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds101 |
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