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Quercetin increased the antiproliferative activity of green tea polyphenol (−)-epigallocatechin gallate in prostate cancer cells

We previously demonstrated that 50% of (−)-epigallocatechin gallate (EGCG) was present in methylated form (4″-MeEGCG) in human prostate tissue, which is less bioactive. We therefore investigated whether quercetin, a natural inhibitor of catechol-O-methyl transferase (COMT), will inhibit EGCG methyla...

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Autors principals: Wang, Piwen, Heber, David, Henning, Susanne M.
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3363324/
https://ncbi.nlm.nih.gov/pubmed/22452782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/01635581.2012.661514
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