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Extension of Chronological Lifespan by Hexokinase Mutation in Kluyveromyces lactis Involves Increased Level of the Mitochondrial Chaperonin Hsp60

Oxidative damage, mitochondrial dysfunction, genomic instability, and telomere shortening represent all molecular processes proposed as causal factors in aging. Lifespan can be increased by metabolism through an influence on such processes. Glucose reduction extends chronological lifespan (CLS) of S...

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Библиографические подробности
Главные авторы: Rizzetto, Lisa, Zanni, Elena, Uccelletti, Daniela, Ferrero, Ileana, Goffrini, Paola
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362934/
https://ncbi.nlm.nih.gov/pubmed/22675632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/946586
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