Pituitary Adenylate Cyclase-Activating Polypeptide Causes Tyrosine Phosphorylation of the Epidermal Growth Factor Receptor in Lung Cancer Cells

Pituitary adenylate cyclase-activating polypeptide (PACAP) is an autocrine growth factor for some lung cancer cells. The activated PACAP receptor (PAC1) causes phosphatidylinositol turnover, elevates cAMP, and increases the proliferation of lung cancer cells. PAC1 and epidermal growth factor recepto...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Moody, Terry W., Osefo, Nauramy, Nuche-Berenguer, Bernardo, Ridnour, Lisa, Wink, David, Jensen, Robert T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The American Society for Pharmacology and Experimental Therapeutics 2012
Pynciau:
Cellular and Molecular
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362890/
https://ncbi.nlm.nih.gov/pubmed/22389426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.190033
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