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Corticotropin, lipotropin, and beta-endorphin production by a human nonpituitary tumor in culture: evidence for a common precursor.

A continuous line (DMS-79) of human pulmonary small cell carcinoma cells was shown to secrete immunoreactive adrenocorticotropin (ACTH), lipotropin, and beta-endorphin concomitantly into the culture medium. Gel filtration of the culture medium demonstrated at least five components: high molecular we...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Bertagna, X Y, Nicholson, W E, Sorenson, G D, Pettengill, O S, Mount, C D, Orth, D N
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1978
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336284/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/217015/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.10.5160
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