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Biological significance of alloreactivity: T cells stimulated by Sendai virus-coated syngeneic cells specifically lyse allogeneic target cells.

In vitro stimulation of spleen cells from mice immune to Sendai virus results in the generation of effector cells that lyse unmodified allogeneic target cells in addition to syngeneic cells modified by virus. These cells are immunologically specific because their lysis may be blocked by cold targets...

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Bibliographic Details
Main Authors: Finberg, R, Burakoff, S J, Cantor, H, Benacerraf, B
Format: Artigo
Language:Inglês
Published: 1978
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC336281/
https://ncbi.nlm.nih.gov/pubmed/217013
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