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Eculizumab as rescue therapy for atypical hemolytic uremic syndrome with normal platelet count

BACKGROUND: Atypical hemolytic uremic syndrome (aHUS) in childhood is a rare disease with frequent progression to end-stage renal disease and a high recurrence after kidney transplantation. Eculizumab, a humanized monoclonal antibody that binds to complement protein C5, may be beneficial in the trea...

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Main Authors: Dorresteijn, Eiske M., van de Kar, Nicole C. A. J., Cransberg, Karlien
Formato: Artigo
Idioma:Inglês
Publicado: Springer-Verlag 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362716/
https://ncbi.nlm.nih.gov/pubmed/22399074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00467-012-2130-z
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