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Aberrant methylation in promoter-associated CpG islands of multiple genes in chronic myelogenous leukemia blast crisis

Chronic myelogenous leukemia (CML) has a typical progressive course with transition from a chronic phase to a terminal blast crisis phase. The mechanisms that lead to disease progression remain to be elucidated. To understand the role of aberrant methylation in the progression of CML, DNA methylatio...

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Main Authors: UEHARA, EISUKE, TAKEUCHI, SEISHO, YANG, YANG, FUKUMOTO, TETSUYA, MATSUHASHI, YOSHIKO, TAMURA, TAKAHIRO, MATSUSHITA, MASAHIDE, NAGAI, MASAMI, KOEFFLER, H. PHILLIP, TASAKA, TAIZO
Formato: Artigo
Idioma:Inglês
Publicado: D.A. Spandidos 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362479/
https://ncbi.nlm.nih.gov/pubmed/22740879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2011.419
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