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Bromodeoxyuridine mutagenesis in mammalian cells: mutagenesis is independent of the amount of bromouracil in DNA.

Studies were undertaken to determine how a line of mutant Syrian hamster melanoma cells (HAB-2E) that displays unlimited growth potential when all of the thymine residues in nuclear DNA are replaced by bromouracil (BrUra) could avoid the deleterious effects of bromodeoxyuridine (BrdUrd) mutagenicity...

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Detalles Bibliográficos
Autores principales: Kaufman, E R, Davidson, R L
Formato: Artigo
Lenguaje:Inglês
Publicado: 1978
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC336246/
https://ncbi.nlm.nih.gov/pubmed/283408
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