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Bromodeoxyuridine mutagenesis in mammalian cells: mutagenesis is independent of the amount of bromouracil in DNA.

Studies were undertaken to determine how a line of mutant Syrian hamster melanoma cells (HAB-2E) that displays unlimited growth potential when all of the thymine residues in nuclear DNA are replaced by bromouracil (BrUra) could avoid the deleterious effects of bromodeoxyuridine (BrdUrd) mutagenicity...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Kaufman, E R, Davidson, R L
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1978
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336246/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/283408/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.10.4982
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