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Dynamic HoxB4-regulatory network during embryonic stem cell differentiation to hematopoietic cells

Efficient in vitro generation of hematopoietic stem cells (HSCs) from embryonic stem cells (ESCs) holds great promise for cell-based therapies to treat hematologic diseases. To date, HoxB4 remains the most effective transcription factor (TF) the overexpression of which in ESCs confers long-term repo...

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Detalhes bibliográficos
Main Authors: Fan, Rong, Bonde, Sabrina, Gao, Peng, Sotomayor, Brendan, Chen, Changya, Mouw, Tyler, Zavazava, Nicholas, Tan, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362371/
https://ncbi.nlm.nih.gov/pubmed/22438249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-12-396754
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