Dynamic HoxB4-regulatory network during embryonic stem cell differentiation to hematopoietic cells

Efficient in vitro generation of hematopoietic stem cells (HSCs) from embryonic stem cells (ESCs) holds great promise for cell-based therapies to treat hematologic diseases. To date, HoxB4 remains the most effective transcription factor (TF) the overexpression of which in ESCs confers long-term repo...

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Main Authors: Fan, Rong, Bonde, Sabrina, Gao, Peng, Sotomayor, Brendan, Chen, Changya, Mouw, Tyler, Zavazava, Nicholas, Tan, Kai
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2012
Teme:
Hematopoiesis and Stem Cells
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362371/
https://ncbi.nlm.nih.gov/pubmed/22438249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-12-396754
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