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Bioluminescence Methodology for the Detection of Protein–Protein Interactions Within the Voltage-Gated Sodium Channel Macromolecular Complex

Protein–protein interactions are critical molecular determinants of ion channel function and emerging targets for pharmacological interventions. Yet, current methodologies for the rapid detection of ion channel macromolecular complexes are still lacking. In this study we have adapted a split-lucifer...

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Detalhes bibliográficos
Main Authors: Shavkunov, Alexander, Panova, Neli, Prasai, Anesh, Veselenak, Ron, Bourne, Nigel, Stoilova-McPhie, Svetla, Laezza, Fernanda
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362325/
https://ncbi.nlm.nih.gov/pubmed/22364545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/adt.2011.413
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