Tirapazamine-Doxorubicin Interaction Referring to Heart Oxidative Stress and Ca(2+) Balance Protein Levels

Doxorubicin (DOX) causes long-term cardiomyopathy that is dependent on oxidative stress and contractility disorders. Tirapazamine (TP), an experimental adjuvant drug, passes the same red-ox transformation as DOX. The aim of the study was to evaluate an effect of tirapazamine on oxidative stress, con...

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Detalhes bibliográficos
Main Authors: Sliwinska, Justyna, Dudka, Jaroslaw, Korga, Agnieszka, Burdan, Franciszek, Matysiak, Wlodzimierz, Jodlowska-Jedrych, Barbara, Mandziuk, Slawomir, Dawidek-Pietryka, Katarzyna
Formato: Artigo
Idioma:Inglês
Publicado em: Oxidative Medicine and Cellular Longevity 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362211/
https://ncbi.nlm.nih.gov/pubmed/22666522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/890826
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