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A polypeptide in eukaryotic initiation factors that crosslinks specifically to the 5'-terminal cap in mRNA.

Protein synthesis initiation factors prepared from rabbit reticulocyte and mouse ascites ribosomes were tested for the ability to crosslink to the 5' cap of mRNA. Crosslinking of one polypeptide of apparent molecular weight 24,000 was inhibited by the cap analogs, m7GMP and m7GDP, indicating a...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Sonenberg, N, Morgan, M A, Merrick, W C, Shatkin, A J
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1978
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336217/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/217002/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.10.4843
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