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Coenzyme Q(1) as a probe for mitochondrial complex I activity in the intact perfused hyperoxia-exposed wild-type and Nqo1-null mouse lung

Previous studies showed that coenzyme Q(1) (CoQ(1)) reduction on passage through the rat pulmonary circulation was catalyzed by NAD(P)H:quinone oxidoreductase 1 (NQO1) and mitochondrial complex I, but that NQO1 genotype was not a factor in CoQ(1) reduction on passage through the mouse lung. The aim...

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Detalhes bibliográficos
Main Authors: Bongard, Robert D., Myers, Charles R., Lindemer, Brian J., Baumgardt, Shelley, Gonzalez, Frank J., Merker, Marilyn P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362155/
https://ncbi.nlm.nih.gov/pubmed/22268123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00251.2011
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