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Activating autoantibodies to the angiotensin II type I receptor play an important role in mediating hypertension in response to adoptive transfer of CD4(+) T lymphocytes from placental ischemic rats
Hypertension in rats with chronic placental ischemia (reduced uterine perfusion pressure, RUPP) is associated with elevated inflammatory cytokines, agonistic autoantibodies to the angiotensin II type I receptor (AT1-AA) and CD4(+) T cells; all of which are elevated in preclamptic women. Additionally...
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| Main Authors: | , , , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Physiological Society
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3362148/ https://ncbi.nlm.nih.gov/pubmed/22461177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00623.2011 |
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