Angiotensin II type 2 receptor-coupled nitric oxide production modulates free radical availability and voltage-gated Ca(2+) currents in NTS neurons

The medial region of the nucleus tractus solitarius (mNTS) is a key brain stem site controlling cardiovascular function, wherein ANG II modulates neuronal L-type Ca(2+) currents via activation of ANG II type 1 receptors (AT(1)R) and production of reactive oxygen species (ROS). ANG II type 2 receptor...

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Autori principali: Wang, Gang, Coleman, Christal G., Glass, Michael J., Zhou, Ping, Yu, Qi, Park, Laibaik, Anrather, Josef, Pickel, Virginia M., Iadecola, Costantino
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2012
Soggetti:
Neural Control
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362142/
https://ncbi.nlm.nih.gov/pubmed/22378773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00571.2011
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