Insulin Receptor Expression and Activity in the Brains of Nondiabetic Sporadic Alzheimer's Disease Cases

We investigated the contents of the insulin receptor-beta subunit (IRβ) and [Tyr1162/1163]-phosphorylated IRβ as surrogate indices of total IR content and IR activation in postmortem hippocampal formation brain specimens from nondiabetic sporadic Alzheimer's disease (AD) cases. We found no sign...

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Autors principals: Ho, Lap, Yemul, Shrishailam, Knable, Lindsay, Katsel, Pavel, Zhao, Rudy, Haroutunian, Vahram, Pasinetti, Giulio Maria
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362009/
https://ncbi.nlm.nih.gov/pubmed/22666619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/321280
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