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A Toll-Spätzle Pathway in the Tobacco Hornworm, Manduca sexta

Insects synthesize a battery of antimicrobial peptides (AMPs) and expression of AMP genes is regulated by the Toll and Imd (immune deficiency) pathways in Drosophila melanogaster. Drosophila Toll pathway is activated after Spätzle (Spz) is cleaved by Spätzle processing enzyme (SPE) to release the ac...

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Detalhes bibliográficos
Main Authors: Zhong, Xue, Xu, Xiao-Xia, Yi, Hui-Yu, Lin, Christopher, Yu, Xiao-Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361650/
https://ncbi.nlm.nih.gov/pubmed/22516181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ibmb.2012.03.009
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