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Benzothiazoles as probes for the 5HT(1A) receptor and the serotonin transporter (SERT): A search for new dual-acting agents as potential antidepressants
The synthesis and evaluation of several benzothiazole based compounds are described in an attempt to identify novel dual-acting 5HT(1A) receptor and SERT inhibitors as new antidepressants. Binding affinities at the 5HT(1A) receptor and the serotonin transporter do not appear to be congruent and othe...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3361616/ https://ncbi.nlm.nih.gov/pubmed/22520153 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2012.03.042 |
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