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Weight loss in obese older adults increases serum sclerostin and impairs hip geometry but both are prevented by exercise training()

We reported that weight loss induces bone loss which is prevented by exercise training; however, the mechanism for this observation remains unclear. Sclerostin, an inhibitor of bone formation, has been found to increase in states of unloading and may mediate the changes in bone metabolism associated...

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Hlavní autoři: Armamento-Villareal, Reina, Sadler, Corinn, Napoli, Nicola, Shah, Krupa, Chode, Suresh, Sinacore, David R, Qualls, Clifford, Villareal, Dennis T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361603/
https://ncbi.nlm.nih.gov/pubmed/22392834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.1560
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