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Nitric oxide increases susceptibility of toll-like receptor-activated macrophages to spreading Listeria monocytogenes

Toll-like receptor (TLR) stimulation activates macrophages to resist intracellular pathogens. Yet, the intracellular bacterium Listeria monocytogenes (Lm) causes lethal infections in spite of innate immune cell activation. Lm uses direct cell-cell spread to disseminate within its host. Here, we have...

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Hlavní autoři: Cole, Caroline, Thomas, Stacey, Filak, Holly, Henson, Peter M., Lenz, Laurel L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361567/
https://ncbi.nlm.nih.gov/pubmed/22542147
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2012.03.011
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