Mechanical ventilation with high tidal volumes attenuates myocardial dysfunction by decreasing cardiac edema in a rat model of LPS-induced peritonitis

BACKGROUND: Injurious mechanical ventilation (MV) may augment organ injury remote from the lungs. During sepsis, myocardial dysfunction is common and increased endothelial activation and permeability can cause myocardial edema, which may, among other factors, hamper myocardial function. We investiga...

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Bibliografiske detaljer
Main Authors: Smeding, Lonneke, Plötz, Frans B, Lamberts, Regis R, van der Laarse, Willem J, Kneyber, Martin CJ, Groeneveld, AB Johan
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361474/
https://ncbi.nlm.nih.gov/pubmed/22433071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-13-23
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