Wnt signaling induces proliferation of sensory precursors in the postnatal mouse cochlea

Inner ear hair cells are specialized sensory cells essential for auditory function. Previous studies have shown that the sensory epithelium is postmitotic, but it harbors cells that can behave as progenitor cells in vitro, including the ability to form new hair cells. Lgr5, a Wnt target gene, marks...

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Bibliografiske detaljer
Main Authors: Chai, Renjie, Kuo, Bryan, Wang, Tian, Liaw, Eric J., Xia, Anping, Jan, Taha A., Liu, Zhiyong, Taketo, Makoto M., Oghalai, John S., Nusse, Roeland, Zuo, Jian, Cheng, Alan G.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361451/
https://ncbi.nlm.nih.gov/pubmed/22562792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1202774109
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