Choline-releasing glycerophosphodiesterase EDI3 drives tumor cell migration and metastasis

Metastasis from primary tumors remains a major problem for tumor therapy. In the search for markers of metastasis and more effective therapies, the tumor metabolome is relevant because of its importance to the malignant phenotype and metastatic capacity of tumor cells. Altered choline metabolism is...

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Detalles Bibliográficos
Autores principales: Stewart, Joanna D., Marchan, Rosemarie, Lesjak, Michaela S., Lambert, Joerg, Hergenroeder, Roland, Ellis, James K., Lau, Chung-Ho, Keun, Hector C., Schmitz, Gerd, Schiller, Juergen, Eibisch, Mandy, Hedberg, Christian, Waldmann, Herbert, Lausch, Ekkehart, Tanner, Berno, Sehouli, Jalid, Sagemueller, Jens, Staude, Hagen, Steiner, Eric, Hengstler, Jan G.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2012
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361409/
https://ncbi.nlm.nih.gov/pubmed/22570503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117654109
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