Choline-releasing glycerophosphodiesterase EDI3 drives tumor cell migration and metastasis

Metastasis from primary tumors remains a major problem for tumor therapy. In the search for markers of metastasis and more effective therapies, the tumor metabolome is relevant because of its importance to the malignant phenotype and metastatic capacity of tumor cells. Altered choline metabolism is...

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Hlavní autoři: Stewart, Joanna D., Marchan, Rosemarie, Lesjak, Michaela S., Lambert, Joerg, Hergenroeder, Roland, Ellis, James K., Lau, Chung-Ho, Keun, Hector C., Schmitz, Gerd, Schiller, Juergen, Eibisch, Mandy, Hedberg, Christian, Waldmann, Herbert, Lausch, Ekkehart, Tanner, Berno, Sehouli, Jalid, Sagemueller, Jens, Staude, Hagen, Steiner, Eric, Hengstler, Jan G.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2012
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361409/
https://ncbi.nlm.nih.gov/pubmed/22570503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117654109
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