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MicroRNA-29 Regulates T-Box Transcription Factors and Interferon-γ Production in Helper T Cells

MicroRNA (miRNA)-deficient helper T cells exhibit abnormal IFN-γ production and decreased proliferation. However, the contributions of individual miRNAs to this phenotype remain poorly understood. We conducted a screen for miRNA function in primary T cells and identified individual miRNAs that rescu...

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Detalhes bibliográficos
Main Authors: Steiner, David F., Thomas, Molly F., Hu, Joyce K., Yang, Zhiyong, Babiarz, Joshua E., Allen, Christopher D.C., Matloubian, Mehrdad, Blelloch, Robert, Ansel, K. Mark
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3361370/
https://ncbi.nlm.nih.gov/pubmed/21820330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2011.07.009
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