Increased gene copy number of ERG on chromosome 21 but not TMPRSS2–ERG fusion predicts outcome in prostatic adenocarcinomas

The role of TMPRSS2–ERG gene fusion in prostate cancer prognostication remains controversial. We evaluated the prognostic role of TMPRSS2–ERG fusion using fluorescence in situ hybridization analysis in a case–control study nested in The Johns Hopkins retropubic radical prostatectomy cohort. In all,...

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Autori principali: Toubaji, Antoun, Albadine, Roula, Meeker, Alan K, Isaacs, William B, Lotan, Tamara, Haffner, Michael C, Chaux, Alcides, Epstein, Jonathan I, Han, Misop, Walsh, Patrick C, Partin, Alan W, De Marzo, Angelo M, Platz, Elizabeth A, Netto, George J
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360950/
https://ncbi.nlm.nih.gov/pubmed/21743434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2011.111
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