Genome-wide association study reveals class I MHC–restricted T cell–associated molecule gene (CRTAM) variants interact with vitamin D levels to affect asthma exacerbations

BACKGROUND: It has recently been shown that vitamin D deficiency can increase asthma development and severity and that variations in vitamin D receptor genes are associated with asthma susceptibility. OBJECTIVE: We sought to find genetic factors that might interact with vitamin D levels to affect th...

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Autori principali: Du, Rose, Litonjua, Augusto A., Tantisira, Kelan G., Lasky-Su, Jessica, Sunyaev, Shamil R., Klanderman, Barbara J., Celedón, Juan C., Avila, Lydiana, Soto-Quiros, Manuel E., Weiss, Scott T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360942/
https://ncbi.nlm.nih.gov/pubmed/22051697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2011.09.034
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