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Cosmids: a type of plasmid gene-cloning vector that is packageable in vitro in bacteriophage lambda heads.

Evidence is presented that ColE1 hybrid plasmids carrying the cohesive-end site (cos) of lambda can be used as gene cloning vectors in conjunction with the lambda in vitro packaging system of Hohn and Murray [(1977) Proc. Natl. Acad. Sci. USA 74, 3259--3263]. Due to the requirement for a large DNA m...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Collins, J, Hohn, B
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1978
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336088/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/360212/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.75.9.4242
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