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Arachidonate 5 Lipoxygenase Expression in Papillary Thyroid Carcinoma Promotes Invasion via MMP-9 Induction

Arachidonate 5-lipoxygenase (ALOX5) expression and activity has been implicated in tumor pathogenesis, yet its role in papillary thyroid carcinoma (PTC) has not been characterized. ALOX5 protein and mRNA were upregulated in PTC compared to matched, normal thyroid tissue, and ALOX5 expression correla...

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Détails bibliographiques
Auteurs principaux: Kummer, Nicolas T., Nowicki, Theodore S, Azzi, Jean Paul, Reyes, Ismael, Iacob, Codrin, Xie, Suqing, Swati, Ismatun, Suslina, Nina, Schantz, Stimson, Tiwari, Raj K., Geliebter, Jan
Format: Artigo
Langue:Inglês
Publié: 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360809/
https://ncbi.nlm.nih.gov/pubmed/22253131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.24069
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