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Internal Ribosomal Entry Site-Mediated Translation Is Important for Rhythmic PERIOD1 Expression

The mouse PERIOD1 (mPER1) plays an important role in the maintenance of circadian rhythm. Translation of mPer1 is directed by both a cap-dependent process and cap-independent translation mediated by an internal ribosomal entry site (IRES) in the 5′ untranslated region (UTR). Here, we compared mPer1...

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Autors principals: Lee, Kyung-Ha, Kim, Sung-Hoon, Kim, Do-Yeon, Kim, Seunghwan, Kim, Kyong-Tai
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360671/
https://ncbi.nlm.nih.gov/pubmed/22662251
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037936
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