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Internal Ribosomal Entry Site-Mediated Translation Is Important for Rhythmic PERIOD1 Expression
The mouse PERIOD1 (mPER1) plays an important role in the maintenance of circadian rhythm. Translation of mPer1 is directed by both a cap-dependent process and cap-independent translation mediated by an internal ribosomal entry site (IRES) in the 5′ untranslated region (UTR). Here, we compared mPer1...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3360671/ https://ncbi.nlm.nih.gov/pubmed/22662251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037936 |
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