2D and 3D-Organized Cardiac Cells Shows Differences in Cellular Morphology, Adhesion Junctions, Presence of Myofibrils and Protein Expression

Cardiac cells are organized in vivo in a complex tridimensional structural organization that is crucial for heart function. While in vitro studies can reveal details about cardiac cell biology, usually cells are grown on simplified two-dimensional (2D) environments. To address these differences, we...

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Главные авторы: Soares, Carolina Pontes, Midlej, Victor, de Oliveira, Maria Eduarda Weschollek, Benchimol, Marlene, Costa, Manoel Luis, Mermelstein, Cláudia
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2012
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360656/
https://ncbi.nlm.nih.gov/pubmed/22662278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038147
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