Hyaluronan Binding Motifs of USP17 and SDS3 Exhibit Anti-Tumor Activity

BACKGROUND: We previously reported that the USP17 deubiquitinating enzyme having hyaluronan binding motifs (HABMs) interacts with human SDS3 (suppressor of defective silencing 3) and specifically deubiquitinates Lys-63 branched polyubiquitination of SDS3 resulting in negative regulation of histone d...

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Detalhes bibliográficos
Main Authors: Ramakrishna, Suresh, Suresh, Bharathi, Bae, Su-Mi, Ahn, Woong-Shick, Lim, Key-Hwan, Baek, Kwang-Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360616/
https://ncbi.nlm.nih.gov/pubmed/22662218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037772
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