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Urine concentrating mechanism: impact of vascular and tubular architecture and a proposed descending limb urea-Na(+) cotransporter

We extended a region-based mathematical model of the renal medulla of the rat kidney, previously developed by us, to represent new anatomic findings on the vascular architecture in the rat inner medulla (IM). In the outer medulla (OM), tubules and vessels are organized around tightly packed vascular...

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Autors principals: Layton, Anita T., Dantzler, William H., Pannabecker, Thomas L.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360582/
https://ncbi.nlm.nih.gov/pubmed/22088433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00263.2011
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