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Urine concentrating mechanism: impact of vascular and tubular architecture and a proposed descending limb urea-Na(+) cotransporter

We extended a region-based mathematical model of the renal medulla of the rat kidney, previously developed by us, to represent new anatomic findings on the vascular architecture in the rat inner medulla (IM). In the outer medulla (OM), tubules and vessels are organized around tightly packed vascular...

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Autori principali: Layton, Anita T., Dantzler, William H., Pannabecker, Thomas L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360582/
https://ncbi.nlm.nih.gov/pubmed/22088433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00263.2011
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