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Detection of carcinogens as mutagens in the Salmonella/microsome test: assay of 300 chemicals: discussion.

About 300 carcinogens and non-carcinogens of a wide variety of chemical types have been tested for mutagenicity in the simple Salmonella/microsome test. The test uses bacteria as sensitive indicators of DNA damage, and mammalian liver extracts for metabolic conversion of carcinogens to their active...

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Библиографические подробности
Опубликовано в::Proc Natl Acad Sci U S A
Главные авторы: McCann, J, Ames, B N
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 1976
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336038/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/768988/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.3.950
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