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Curcumin attenuates Nrf2 signaling defect, oxidative stress in muscle and glucose intolerance in high fat diet-fed mice

AIM: To investigate the signaling mechanism of anti-oxidative action by curcumin and its impact on glucose disposal. METHODS: Male C57BL/6J mice were fed with either a normal diet (n = 10) or a high fat diet (HFD) (n = 20) to induce obesity and insulin resistance. After 16 wk, 10 HFD-fed mice were f...

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Main Authors: He, Hui-Jun, Wang, Guo-Yu, Gao, Yuan, Ling, Wen-Hua, Yu, Zhi-Wen, Jin, Tian-Ru
Formato: Artigo
Idioma:Inglês
Publicado: Baishideng Publishing Group Co., Limited 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360224/
https://ncbi.nlm.nih.gov/pubmed/22645638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4239/wjd.v3.i5.94
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