Full-Exon Pyrosequencing Screening of BRCA Germline Mutations in Mexican Women with Inherited Breast and Ovarian Cancer

Hereditary breast cancer comprises 10% of all breast cancers. The most prevalent genes causing this pathology are BRCA1 and BRCA2 (breast cancer early onset 1 and 2), which also predispose to other cancers. Despite the outstanding relevance of genetic screening of BRCA deleterious variants in patien...

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Detalhes bibliográficos
Main Authors: Vaca-Paniagua, Felipe, Alvarez-Gomez, Rosa María, Fragoso-Ontiveros, Verónica, Vidal-Millan, Silvia, Herrera, Luis Alonso, Cantú, David, Bargallo-Rocha, Enrique, Mohar, Alejandro, López-Camarillo, César, Pérez-Plasencia, Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360054/
https://ncbi.nlm.nih.gov/pubmed/22655046
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037432
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