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The ter Mutation in the Rat Dnd1 Gene Initiates Gonadal Teratomas and Infertility in Both Genders

A spontaneous mutation leading to the formation of congenital ovarian and testicular tumors was detected in the WKY/Ztm rat strain. The histological evaluation revealed derivatives from all three germ layers, thereby identifying these tumors as teratomas. Teratocarcinogenesis was accompanied by infe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Northrup, Emily, Zschemisch, Nils-Holger, Eisenblätter, Regina, Glage, Silke, Wedekind, Dirk, Cuppen, Edwin, Dorsch, Martina, Hedrich, Hans-Jürgen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360017/
https://ncbi.nlm.nih.gov/pubmed/22655094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038001
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