Proteomic Signatures of the Desmoplastic Invasion Front Reveal Collagen Type XII as a Marker of Myofibroblastic Differentiation During Colorectal Cancer Metastasis

Cancer-associated fibroblasts (CAFs), represent a pivotal compartment of solid cancers (desmoplasia), and are causatively implicated in cancer development and progression. CAFs are recruited by growth factors secreted by cancer cells and they present a myofibroblastic phenotype, similar to the one o...

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Detalhes bibliográficos
Main Authors: Karagiannis, George S., Petraki, Constantina, Prassas, Ioannis, Saraon, Punit, Musrap, Natasha, Dimitromanolakis, Apostolos, Diamandis, Eleftherios P.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2012
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359884/
https://ncbi.nlm.nih.gov/pubmed/22408128
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