Antagonism of 5-hydroxykynurenamine against serotonin action on platelet aggregation.
Serotonin induced an aggregation of human platelets, whereas 5-hydroxykynurenamine, produced from serotonin by the action of indoleamine 2,3-dioxygenase, did not cause any significant degree of platelet aggregation. 5-Hydroxykynurenamine specifically inhibited both a serotonin-induced aggregation of...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1976
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC335967/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1061163/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.2.643 |
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