Antagonism of 5-hydroxykynurenamine against serotonin action on platelet aggregation.

Serotonin induced an aggregation of human platelets, whereas 5-hydroxykynurenamine, produced from serotonin by the action of indoleamine 2,3-dioxygenase, did not cause any significant degree of platelet aggregation. 5-Hydroxykynurenamine specifically inhibited both a serotonin-induced aggregation of...

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Bibliografiske detaljer
Main Authors: Okuma, M, Tokuyama, T, Senoh, S, Hirata, F, Hayaishi, O
Format: Artigo
Sprog:Inglês
Udgivet: 1976
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC335967/
https://ncbi.nlm.nih.gov/pubmed/1061163
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