Dietary Vitamin D(3) and 1,25-Dihydroxyvitamin D(3) (Calcitriol) Exhibit Equivalent Anticancer Activity in Mouse Xenograft Models of Breast and Prostate Cancer

1,25-dihydroxyvitamin D(3) [1,25(OH)(2)D(3) or calcitriol], the hormonally active vitamin D metabolite, exhibits anticancer actions in models of breast cancer and prostate cancer. Because CYP27B1 (1α-hydroxylase), the enzyme catalyzing 1,25(OH)(2)D(3) formation in the kidney, is also expressed in ex...

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Detalhes bibliográficos
Main Authors: Swami, Srilatha, Krishnan, Aruna V., Wang, Jennifer Y., Jensen, Kristin, Horst, Ronald, Albertelli, Megan A., Feldman, David
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2012
Assuntos:
Cancer-Oncogenes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359605/
https://ncbi.nlm.nih.gov/pubmed/22454149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-1600
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