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Identification of mutagenic metabolites of benzo(a)pyrene in mammalian cells.

The mutagenicity of benzo[a]pyrene and 15 of its derivatives, which included phenols, the benzo[a]yrene-4,5-epoxide (the K-region epoxide), dihydrodiols, two isomeric 7,8-diol-9,10-epoxides, a 6-methyl derivative, and a 6-hydroxymethyl derivative, were tested with Chinese hamster V79 cells in order...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Huberman, E, Sachs, L, Yang, S K, Gelboin, V
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1976
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC335960/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1061161/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.2.607
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