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Inhibition of tumor cell proliferation by dimerized ribonuclease.

A cross-linked dimer of pancreatic ribonuclease A (ribonucleate 3'-pyrimidino-olitonucleotidohydrolase, EC 3.1.4.22), at a 10 mg/liter concentration, blocks proliferation of tumor cells. The protein retains this ability after inactivation by iodoacetate. The cytostatic effect of ribonuclease pr...

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Main Authors: Bartholeyns, J, Baudhuin, P
格式: Artigo
語言:Inglês
出版: 1976
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC335952/
https://ncbi.nlm.nih.gov/pubmed/174114
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