The emerging role of autophagy in the pathophysiology of diabetes mellitus

An emerging body of evidence supports a role for autophagy in the pathophysiology of type 1 and type 2 diabetes mellitus. Persistent high concentrations of glucose lead to imbalances in the antioxidant capacity within the cell resulting in oxidative stress-mediated injury in both disorders. An antic...

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Main Authors: Gonzalez, Claudio D, Lee, Myung-Shik, Marchetti, Piero, Pietropaolo, Massimo, Towns, Roberto, Vaccaro, Maria I, Watada, Hirotaka, Wiley, John W
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2011
Teme:
Review
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359481/
https://ncbi.nlm.nih.gov/pubmed/20935516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.7.1.13044
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