Molecular mechanism of inhibition of firefly luminescence by local anesthetics.

The kinetics of the action of local anesthetics upon firefly luciferin and luciferase systems is presented. Clinical concentrations of local anesthetics inhibited this ATP-induced luminescence in a dose-dependent manner. From the effects of temperature and pH upon the inhibitory action of the local...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Ueda, I, Kamaya, H, Eyring, H
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1976
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC335933/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1759/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.73.2.481
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