Mutations in the potassium channel subunit KCNE1 are associated with early-onset familial atrial fibrillation

BACKGROUND: Atrial fibrillation (AF) is the most common arrhythmia. The potassium current I(Ks )is essential for cardiac repolarization. Gain-of-function mutations in K(V)7.1, the pore-forming α-subunit of the I(Ks )channel, have been associated with AF. We hypothesized that early-onset lone AF is a...

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Main Authors: Olesen, Morten S, Bentzen, Bo H, Nielsen, Jonas B, Steffensen, Annette B, David, Jens-Peter, Jabbari, Javad, Jensen, Henrik K, Haunsø, Stig, Svendsen, Jesper H, Schmitt, Nicole
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359244/
https://ncbi.nlm.nih.gov/pubmed/22471742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-13-24
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