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Predicting tissue specific cis-regulatory modules in the human genome using pairs of co-occurring motifs

BACKGROUND: Researchers seeking to unlock the genetic basis of human physiology and diseases have been studying gene transcription regulation. The temporal and spatial patterns of gene expression are controlled by mainly non-coding elements known as cis-regulatory modules (CRMs) and epigenetic facto...

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Main Authors: Girgis, Hani Z, Ovcharenko, Ivan
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359238/
https://ncbi.nlm.nih.gov/pubmed/22313678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-25
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