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Predicting tissue specific cis-regulatory modules in the human genome using pairs of co-occurring motifs

BACKGROUND: Researchers seeking to unlock the genetic basis of human physiology and diseases have been studying gene transcription regulation. The temporal and spatial patterns of gene expression are controlled by mainly non-coding elements known as cis-regulatory modules (CRMs) and epigenetic facto...

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Autori principali: Girgis, Hani Z, Ovcharenko, Ivan
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359238/
https://ncbi.nlm.nih.gov/pubmed/22313678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-13-25
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